Biotechnology
Targeting Individual and Industrial Health
91猎奇 faculty create interventions aimed at the full spectrum of serious illness, from
cardiovascular disease to preterm infant lactation issues. This requires significant
research infrastructure, from understanding fluid flow patterns to physical improvement
of materials for better integration with host tissue.
Our biochemical engineers synthesize antioxidants and antivenom peptides in bacteria and yeast, and develop tools to identify therapeutic genes. Targeting both industrial and clinical applications, diagnostic researchers develop rapid, robust, and inexpensive biosensors for pathogen screening and disease detection, identifying contamination, biofilms, abnormal cells, and blood-based biomarkers.
All of the above is done in close collaboration with medical faculty, entrepreneurs, biomechanical engineers in the Bay Area. Below is a rotating selection of our standout investigators in these areas.
鈼�
鈼� Related Strength: Drug Discovery
鈼� Related Strength: Biomedical Engineering
Selected Publications
Lew, C., et al. (2023). . Chemistry of Materials, 35(15).
Martins, L., Wong, R., Larabee, F., Grillo-Hill, B. (2024). . J. Vis. Exp., (213).
Ouverney, C. C. (2016). . Manual of Environmental Microbiology, Fourth Edition.
Sass, G, Miller Conrad, L. C., Nguyen, T.-T. H., & Stevens, D. A. (2020). . Transactions of the Royal Society of Tropical Medicine and Hygiene, 114(7).
Sobsey, M., Khatib, L., Hill, V., Alocilja, E., & Pillai, S. (2006). . Animal Agriculture and the Environment.
Switz, N., D'Ambrosio, M., & Fletcher, D. (2014). . PLoS ONE, 9(5).
Feinberg, E., VanHoven, M., Bendesky, A., et al., (2008). . Neuron 57(3).
Award Highlights
Grillo-Hill, "Spinning Disk Confocal Microscope" 鈥� National Institute on Alcohol Abuse and Alcoholism (NIAAA), 2024
Ouverney, 鈥淢ARC U*STAR at San Jos茅 State University鈥� 鈥� Department of Health & Human Services, 2020
Ramasubramanian A., Lee, S.J., "Mechanophenotyping RBC subpopulations in ME/CFS" 鈥� NIH, 2025
Ramasubramanian A., Lee, S.J., Lee, W., "Thrombosis in Microgravity" 鈥� NASA, 2020
Singmaster, Ouverney, Rascon, 鈥淪an Jos茅 State University Rise Program鈥� 鈥� Department of Health & Human Services, 2019
Innovations
A method of conducting single-cell analysis.
Smart Breast Pump
A smart robotic breast pump that integrates self-adjusting compression and vacuum
pressures, along with a temperature control system.
Antibiotic Adjuvants for Gram Negative Bacteria
U.S. Provisional Patent Application No. 63/351,737
Antibacterial Adjuvants and Applications Thereof
International Patent Application No. WO 2022/036208
US Patent No. US 11,129,532
US Patent No. US 10,989,907
US Patent No. US 10,745,748
Featured Faculty
Sheryl Ehrman
Dean, Davidson College of Engineering
Aerosol Science and Technology, Particle Technology, Air Pollution
ORCID: 0000-0002-7925-0568
Associate Professor of Biological Sciences
Cancer Cell Biology, Intracellular pH, Drosophila
ORCID: 0000-0001-6471-7025
Leila Khatib
Assistant Professor of Biological Sciences
Water, Wastewater, Recycled Water and Viral Detection Methods
ORCID: 0000-0002-6382-5291
Assistant Professor Chemical and Materials Engineering
Zeolites, Nanoporous Materials, Catalysis, Sustainable Chemicals, Environmental Remediation
ORCID: 0000-0003-4568-4461
Cleber Ouverney
Professor of Biological Sciences
Candidate Division TM7, Uncultured Bacteria, Genetic Diversity, Microbial Communities
ORCID: 0000-0002-4135-7562
Professor of Chemical and Materials Engineering
Mechanobiology, Platelet, Clot, Fibrin, FXIII, Blood Flow, Chronic Fatigue Syndrome
ORCID: 0000-0002-7057-8663
Professor of Physics
Diagnostics, Optics, Microscopy, Fluorescence, Cellphone, Mobile Phone, Tuberculosis,
Loa, Lymphatic Filariasis, Onchocerciasis, Point of Care, Retinal
ORCID: 0000-0002-3639-4588
Associate Dean for Research, College of Science
Neural Circuit Formation, Learning, Memory, Sleep
ORCID: 0000-0001-7714-1555
Potential collaborators and members of the media may contact us at officeofresearch@sjsu.edu.
